ENA Profile Test Price in Bangladesh – 2025 Updated
The ENA Profile Test, also known as the Extractable Nuclear Antigen (ENA) Panel, is a specialized blood test designed to detect autoantibodies associated with autoimmune diseases such as systemic lupus erythematosus (SLE), Sjögren’s syndrome, scleroderma, and mixed connective tissue disease (MCTD). This test is vital for diagnosing and distinguishing between these conditions by identifying antibodies that target proteins in the cell nucleus, such as Ro, La, Sm, RNP, Scl-70, and Jo-1. If you’re experiencing symptoms like persistent fever, fatigue, muscle pain, joint swelling, or skin rashes, and have a positive antinuclear antibody (ANA) test, your doctor may recommend this test. In Bangladesh, the ENA Profile Test price in Bangladesh typically ranges from 8,000 BDT to 20,000 BDT, depending on the diagnostic center and test type (qualitative or quantitative).
What is an ENA Profile Test?
The ENA Profile Test is a blood test that measures the presence of autoantibodies against extractable nuclear antigens (ENAs), proteins found in the cell nucleus that can be extracted using saline solutions. These autoantibodies are produced when the immune system mistakenly attacks the body’s own tissues, leading to autoimmune diseases. The test is highly specific, helping doctors differentiate between various autoimmune conditions based on the antibodies detected. Key antibodies include:
- Anti-Ro (SSA) and Anti-La (SSB): Associated with Sjögren’s syndrome and SLE.
- Anti-Sm: Highly specific for SLE.
- Anti-RNP: Found in mixed connective tissue disease (MCTD).
- Anti-Scl-70: Linked to scleroderma.
- Anti-Jo-1: Associated with polymyositis and dermatomyositis.
The test is often ordered as a follow-up to a positive ANA test when symptoms suggest an autoimmune disorder. Alternative names include the ENA Panel, Anti-ENA Screen, or ANA Profile Test (Mayo Clinic ENA Test).
Clinical Significance
The ENA Profile Test is critical for:
- Diagnosis: Identifying specific autoimmune diseases.
- Differentiation: Distinguishing between conditions with overlapping symptoms.
- Monitoring: Tracking disease progression or response to treatment.
Medical Conditions Requiring the Test
Conditions that may necessitate an ENA Profile Test include:
- Systemic lupus erythematosus (SLE)
- Sjögren’s syndrome
- Scleroderma
- Mixed connective tissue disease (MCTD)
- Polymyositis and dermatomyositis
When is an ENA Profile Test Recommended?
The ENA Profile Test is recommended when a patient exhibits symptoms of an autoimmune disease, particularly after a positive ANA test. It’s used primarily for diagnosis but can also monitor disease activity. Common symptoms prompting this test include:
- Persistent fever and fatigue
- Muscle and joint pain or swelling
- Skin rashes, especially sun-sensitive ones
- Dry eyes and mouth (indicative of Sjögren’s syndrome)
- Raynaud’s phenomenon (color changes in fingers/toes in cold)
- Swelling in hands and feet
Diagnostic Use
Doctors use ENA Profile Test results, combined with clinical symptoms and other lab findings, to confirm or rule out specific autoimmune diseases. For example, a positive Anti-Sm result strongly suggests SLE, while Anti-RNP points to MCTD (Cleveland Clinic ENA Panel).
Screening vs. Monitoring
The test is mainly diagnostic but may be repeated to monitor disease progression or treatment efficacy in patients with confirmed autoimmune conditions.
ENA Profile Test Preparation
The ENA Profile Test requires no special preparation, making it convenient for patients. Key points include:
- Fasting: Not required; you can eat and drink normally.
- Medications: Continue taking prescribed medications unless your doctor advises otherwise.
- Sample Collection: A healthcare professional draws a small blood sample from a vein in your arm, which takes a few minutes. You may feel a brief pinch from the needle.
- Test Duration: The blood draw is quick, but lab analysis may take several days, depending on the facility.
Some medications or underlying conditions might affect results, so inform your doctor about your medical history (Apollo247 ENA Test).
ENA Profile Test Price List in Government Hospitals in Bangladesh
Despite thorough research, no government hospitals in Bangladesh, such as Bangabandhu Sheikh Mujib Medical University (BSMMU) or Dhaka Medical College Hospital (DMCH), appear to offer the ENA Profile Test in their standard price lists. This may be due to the test’s specialized nature, which is more commonly available in private diagnostic centers. Patients seeking this test should contact private facilities or consult their doctor for referrals.
ENA Profile Test Price List in Private Hospitals in Bangladesh
The ENA Profile Test is available at several private diagnostic centers in Bangladesh. Below is a table listing known prices as of 2025:
| Hospital/Diagnostic Center | Location | ENA Profile Test Price (BDT) | Contact Number |
|---|---|---|---|
| Popular Diagnostic Centre Ltd. | English Road, Dhaka | 8,000 | +880258310790 |
| Popular Diagnostic Centre Ltd. | Dhanmondi, Dhaka | 8,000 | +880258310790 |
| Thyrocare Bangladesh Limited | Various locations | 15,000 (Qualitative), 20,000 (Quantitative) | +8801713030303 |
| Enam Medical College Hospital | Savar, Dhaka | Not available | +88027791000 |
| Healthcare Diagnostics Center Ltd. | Dhaka | Not available | +8801713030303 |
| Ibn Sina Diagnostic & Imaging Centre | Dhanmondi, Dhaka | Not available | +8801711629137 |
| Labaid Diagnostic Centre | Dhanmondi, Dhaka | Not available | +8801766662525 |
| Square Hospital Laboratory | Panthapath, Dhaka | Not available | +8801713141447 |
| United Hospital Laboratory | Gulshan, Dhaka | Not available | +8801914001234 |
| Evercare Hospital Dhaka | Bashundhara, Dhaka | Not available | +8801841121416 |
Note: Prices may vary, and some centers may offer home sample collection or discounts. Contact the facility directly to confirm current pricing and availability (Popular Diagnostic).
Understanding ENA Profile Test Results
ENA Profile Test results are reported as positive or negative for each antibody tested. Here’s what they mean:
- Normal Range: Negative for all antibodies, indicating no detectable autoantibodies.
- Abnormal Results: Positive for one or more antibodies, suggesting an autoimmune disease. Examples:
- Anti-Sm: Strongly indicative of SLE.
- Anti-RNP: Suggests MCTD.
- Anti-Scl-70: Points to scleroderma.
- Anti-Jo-1: Associated with polymyositis/dermatomyositis.
Factors Affecting Results
Several factors may influence test outcomes:
- Medications: Certain drugs can alter antibody levels, potentially leading to false positives or negatives.
- Other Autoimmune Conditions: Coexisting autoimmune diseases may complicate interpretation.
- Disease Stage: Early in the disease, antibody levels may be too low to detect, resulting in false negatives.
When to Consult a Doctor
Always discuss results with your doctor, who will interpret them in the context of your symptoms, medical history, and other tests. If results are negative but symptoms persist, your doctor may recommend repeating the test or exploring other diagnostic options (Testing.com ENA Panel).
Frequently Asked Questions
What is the accuracy of the ENA Profile Test?
The test is highly specific for certain antibodies (e.g., Anti-Sm for SLE) but less so for others. Accuracy depends on the disease and clinical context, and results should be interpreted with symptoms (South Tees NHS).
How long does it take to get ENA Profile Test results?
Results typically take 3–7 days, depending on the lab. For example, Thyrocare Bangladesh processes samples in India, which may extend the turnaround time (Thyrocare Bangladesh).
Is the ENA Profile Test covered by insurance in Bangladesh?
Coverage varies by insurance provider. Check with your insurer to confirm if autoimmune diagnostic tests are included (Redcliffe Labs).
How often should the ENA Profile Test be done?
It’s usually performed once for diagnosis but may be repeated to monitor disease activity or treatment response, as advised by your doctor.
What’s the difference between the ENA Profile Test and the ANA Test?
The ANA Test is a broad screening tool for autoimmune diseases, while the ENA Profile Test is a follow-up that identifies specific antibodies to pinpoint conditions (Lab Tests Online UK).
Can the ENA Profile Test be done at home?
No, it requires a blood sample drawn by a professional and analyzed in a lab. Some centers offer home sample collection (Sasthya Seba).
Are there side effects of the ENA Profile Test?
The test is safe, with minimal risks like slight pain, bruising, or infection at the blood draw site (1mg ENA Test).
Conclusion
The ENA Profile Test is a critical diagnostic tool for identifying autoimmune diseases in Bangladesh, offering clarity for conditions like SLE, Sjögren’s syndrome, and scleroderma. With prices ranging from 8,000 BDT to 20,000 BDT, comparing costs across private diagnostic centers like Popular Diagnostic Centre and Thyrocare Bangladesh is essential for affordability. Since government hospitals do not typically offer this test, private facilities are the go-to option. Consult your healthcare provider to determine if the ENA Profile Test is right for you and to interpret results accurately. For the latest ENA Profile Test price in Bangladesh, contact trusted diagnostic centers and prioritize quality for reliable outcomes.
